The TMC6 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to TMC6. This antibody recognizes Human antigen. The TMC6 Polyclonal Antibody has been validated for the following applications: Immunofluorescence, and Western Blot.
Description
Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs